A video posted online claims to show that Islamic State militants have killed the captured US aid worker Abdul-Rahman Kassig.
In the video, a masked militant stands over a severed head which he says is that of Kassig.
The US says it is working to determine the authenticity of the video, which also shows a mass beheading of Syrian troops.
Kassig, also known as Peter, was captured last year.
His family, who live in the US state of Indiana, said they were awaiting confirmation of the reports about their “treasured son” and had nothing more to say at this time.
Kassig’s parents last month released extracts of a letter written by their son, in which he told of the strains of captivity.
“This is the hardest thing a man can go through, the stress and fear are incredible,” the aid worker wrote.
“They tell us you have abandoned us and/or don’t care but of course we know you are doing everything you can and more.
“Don’t worry Dad, if I do go down, I won’t go thinking anything but what I know to be true. That you and mom love me more than the moon and the stars.”
Kassig was a former US Army Ranger who served in Iraq and later trained as an emergency medical technician, travelling to Lebanon in May 2012 to work in border hospitals treating Palestinian refugees and later those fleeing the Syrian conflict.
Later that year, he founded the Special Emergency Response and Assistance (Sera) organisation and subsequently moved its base of operations to southern Turkey, near the border with Syria.
Kassig sourced and delivered supplies to camps on both sides of the Syrian border, and helped to treat civilian casualties and train medics inside Syria.
He was undertaking a project for Sera when he was captured in October 2013 while travelling to eastern Syria.